产品货号:
Z32278
中文名称:
APBB1抗体
英文名称:
Anti-APBB1 Antibody (Clone#23A71)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-APBB1 Antibody (Clone#23A71) |
指标别名 | APBB1;FE65;Protein Fe65;RIR |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,ICC/IF |
基因名称 | APBB1 |
克隆号 | 23A71 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human FE65 |
实际分子量 | 77KD/100KD |
成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | APBB1 is also known as RIR or FE65.The protein encoded by this gene is a member of the Fe65 protein family.It is an adaptor protein localized in the nucleus.It interacts with the Alzheimer's disease amyloid precursor protein (APP),transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein.APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation.This encoded protein could play an important role in the pathogenesis of Alzheimer's disease.It is thought to regulate transcription.Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression.Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Uniprot ID | O00213 |
基因名全称 | amyloid beta (A4) precursor protein-binding,family B,member 1 (Fe65) |
蛋白名全称 | Amyloid beta A4 precursor protein-binding family B member 1 |
推荐稀释比 | Western blot (WB) 1:500~2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
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